Local transportation in Syracuse (and Ortigia) is good with regular bus and train service. A rental car might be a good idea if you are visiting several nearby towns or remote inland villages.
Catania Fontanarossa Airport (aka Vincenzo Bellini Airport) (CTA)
International airport with direct flights to most of Europe, Moscow, Dubai, and Kiev. No direct North American flights.
Via Fontanarossa, 95121 Catania CT, Italy
Transfers from the airport to Ortigia
Bus service from the airport to Ortigia is available via Interbus. 1 1/4 hour. Website is not exactly user friendly but bus service is reliable.
Just across the bridge from Ortigia. 20 minute walk.
Via Ermocrate, Syracuse, Italy
10 minute walk to Ortigia.
Via Rodi, 11, 96100 Siracusa SR, Italy
Public bus transport in Syracuse. Also operates city to city service. Website is in Italian.
Extremely convenient minibus service around Ortegia and to sites in greater Syracuse.